How Immunotropics Prevent Common Cold?
The Common cold is a term used for mild upper respiratory illnesses, that consists of a heterogeneous group of self-limited diseases caused by several viruses. It is the most widely prevalent health condition throughout the world.
The incidence, severity and duration of common cold can be decreased by maintaining a normal healthy immune defense system.
Physical barriers, innate (inborn) and adaptive (acquired) immunity all get involved during an episode of a common cold. Biavexia – I am Immune drink shot has valuable ingredients that enhance your immunity that helps to prevent and fight against the common cold.
Vitamin A, C and E: Research has shown that vitamins A, C, and E in combination can improve cell-mediated immunity by increasing the number of T lymphocytes cells, T4 cells, and the T4: T8 ratio. These cells directly kill the infected cells, activate other immune cells, regulate the immune response1.
Vitamin C: Vitamin C has a reliable effect in reducing the duration and severity of common cold symptoms. In adults, the duration of colds was shown to have reduced by 8% (3% to 12%) and in children by 14% (7% to 21%). It has a significant radical scavenging effect on physical barriers, increases the activity of the inflammatory cells, and reduces the generation of superoxide radicals2.
B vitamins: The B vitamins such as vitamin B6, vitamin B12 and folate are required as cofactors in several body processes. Studies have shown that they increase the activity of killer cytotoxic cells that protect the body from various infections3.
Green tea extract: Green tea catechins inhibit the adsorption of Influenza virus into infected cells and suppressed its replication and enzymatic activity. Besides, tea catechins enhance your immunity against viral infection. Studies on adults have shown that the consumption of green tea led to a decrease in the incidence of colds4.
Grape seed extract: Grape seed extract is found to have many benefits, including antioxidant, anti-inflammatory, anticancer, and antimicrobial properties. It acts against viruses and bacteria that cause upper respiratory tract infections. Large quantities of phenolic compounds present in grape seed extract such as gallic acid, and polymeric proanthocyanins are responsible for its action5.
Shiitake mushrooms: Lentinula edodes (shiitake) mushrooms improve immunity, as seen by improved cell proliferation and activation and increased production of protective immunoglobulins in a clinical trial on adult healthy males who were given mushrooms for 4 weeks. The levels of inflammatory markers such as cytokines and serum C-reactive protein were decreased by the mushroom treatment6.
N-acetyl cysteine: N-acetyl cysteine has been shown to inhibit the replication of respiratory viruses such as the influenza virus and respiratory syncytial virus both invitro and in adults. It decreases the release of inflammatory mediators during virus infection7.
Glutathione: Numerous conditions of the respiratory tract are linked to oxidative stress and decreased glutathione, both locally in the affected tissues and systemically. The oxidative stress of those conditions may be associated with the depletion of glutathione, that is increased by the higher levels of oxygen in the upper respiratory tract. Studies on adults have reported clinical benefits from the use of an antioxidant or glutathione support8.
R-Lipoic acid: R-Lipoic acid is a powerful antioxidant and widely used for oxidative stress. It has been shown to inhibit the propagation of the influenza virus by decreasing the action of its enzymes9.
In nutshell, the Biavexia – I am Immune drink shot provides essential nutrients that are required for the protection against common cold. In case of persistent or recurrent colds, please consult your health care provider.
- Penn ND, Purkins L, Kelleher J, et al. The effect of dietary supplementation with vitamins A, C and E on cell-mediated immune function in elderly long-stay patients: a randomized controlled trial. Age Ageing. 1991 May;20(3):169-74. doi: 10.1093/ageing/20.3.169.
- Rondanelli M, Miccono A, Lamburgini S, et al. Self-Care for Common Colds: The Pivotal Role of Vitamin D, Vitamin C, Zinc, and Echinacea in Three Main Immune Interactive Clusters (Physical Barriers, Innate and Adaptive Immunity) Involved during an Episode of Common Colds-Practical Advice on Dosages and on the Time to Take These Nutrients/Botanicals in order to Prevent or Treat Common Colds. Evid based complement alternat med.2018; 2018: 5813095. doi:10.1155/2018/5813095.
- Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020;12(1):236. doi:10.3390/nu1201023
- Furushima D, Ide K, Yamada H. Effect of Tea Catechins on Influenza Infection and the Common Cold with a Focus on Epidemiological/Clinical Studies. Molecules. 2018;23(7):1795. doi:10.3390/molecules23071795.
- Su X, D’Souza DH. Grape seed extract for control of human enteric viruses. Appl Environ Microbiol. 2011;77(12):3982-3987. doi:10.1128/AEM.00193-11.
- Dai X, Stanilka MJ, Rowe AC, et al. Consuming Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity: A Randomized Dietary Intervention in Healthy Young Adults. J American Coll Nutr. 2015;34:6, 478-487.doi: 10.1080/07315724.2014.950391.
- Mata M, Morcillo E, Gimeno C, et al. N-acetyl-L-cysteine (NAC) inhibit mucin synthesis and pro-inflammatory mediators in alveolar type II epithelial cells infected with influenza virus A and B and with respiratory syncytial virus (RSV). Biochem Pharmacol. 2011;82(5):548-555.oi:10.1016/j.bcp.2011.05.014.
- Asher BF, Guilford FT. Oxidative Stress and Low Glutathione in Common Ear, Nose, and Throat Conditions: A Systematic Review. Altern Ther Health Med. 2016;22(5):44-50.
- Bai SW, Chen C, Jun J, et al. Inhibition Effect of Alpha-Lipoic Acid on the Propagation of Influenza A Virus in MDCK Cells. Pakistan Vet J. 2012; 32 (1):101-106.